Almost every missionary who is honest with themselves must admit that the ups and downs of missionary life and the stressors of cross-cultural living can take a toll on the body, the heart, and the mind. I remember well some of the extended seasons of low motivation, unwanted cynicism, and sadness…even in the midst of fruitful ministry. As a Christ-centered Biblical counselor, I want to take a wholistic view of depression through an integrated framework that gives full weight